- Feyenoord 2-1 Napoli (Nicolai Jorgensen 33', Jerry St. Juste 90' ; Piotr Zelinski 2')
- Shakhtar Donetsk 2-1 Manchester City (Bernard 26', Ismaily 32' ; Sergio Aguero 90'-penalti)
GRUP G (Klasemen akhir: Besiktas, Porto, Leipzig, Monaco)
- FC Porto 5-2 AS Monaco (Vincent Aboubakar 9', 33', Yacine Brahimi 45', Alex Telles 65', Tiqunho 88' ; Kamil Glik 61'-penalti, Radamel Falcao 78')
- RB Leipzig 1-2 Besiktas (Naby Keita 87' ; Alvaro Negredo 10'-penalti, Anderson Talisca 90')
GRUP H (Klasemen akhir: Tottenham, Madrid, Dortmund, APOEL)
- Tottenham Hotspur 3-0 APOEL Nicosia (Fernando Llorente 20', Son Heung-min 37', George N'Koulou 80')
- Real Madrid 3-2 Borussia Dortmund (Borja Mayoral 8', Cristiano Ronaldo 12', Lucas Vazquez 81' ; Pierre-Emerick Aubameyang 43', 49')