- Arsenal vs Man City
- Aston Villa vs Leicester City
- Brighton vs Crystal Palace
- Burnley vs West Brom
- Fulham vs Sheffield United
- Liverpool vs Everton
- Man Utd vs Newcastle United
- Southampton vs Chelsea
- West Ham vs Spurs
- Wolves vs Leeds United
Sabtu, 27 Februari 2021 (Pekan 26)
- Chelsea vs Man Utd
- Crystal Palace vs Fulham
- Everton vs Southampton
- Leeds United vs Aston Villa
- Leicester City vs Arsenal
- Man City vs West Ham
- Newcastle United vs Wolves
- Sheffield United vs Liverpool
- Spurs vs Burnley
- West Brom vs Brighton
Sabtu, 6 Maret 2021 (Pekan 27)
- Aston Villa vs Wolves
- Brighton vs Leicester City
- Burnley vs Arsenal
- Chelsea vs Everton
- Liverpool vs Fulham
- Man City vs Man Utd
- Sheffield United vs Southampton
- Spurs vs Crystal Palace
- West Brom vs Newcastle United
- West Ham vs Leeds United
Sabtu, 13 Maret 2021 (Pekan 28)
- Arsenal vs Spurs
- Crystal Palace vs West Brom
- Everton vs Burnley
- Fulham vs Man City
- Leeds United vs Chelsea
- Leicester City vs Sheffield United
- Man Utd vs West Ham
- Newcastle United vs Aston Villa
- Southampton vs Brighton
- Wolves vs Liverpool
Sabtu, 20 Maret 2021 (Pekan 29)
- Brighton vs Newcastle United
- Burnley vs Leicester City
- Crystal Palace vs Man Utd
- Fulham vs Leeds United
- Liverpool vs Chelsea
- Man City vs Wolves
- Sheffield United vs Aston Villa
- Spurs vs Southampton
- West Brom vs Everton
- West Ham vs Arsenal
Sabtu, 3 April 2021 (Pekan 30)
- Arsenal vs Liverpool
- Aston Villa vs Fulham
- Chelsea vs West Brom
- Everton vs Crystal Palace
- Leeds United vs Sheffield United
- Leicester City vs Man City
- Man Utd vs Brighton
- Newcastle United vs Spurs
- Southampton vs Burnley
- Wolves vs West Ham
Sabtu, 10 April 2021 (Pekan 31)
- Brighton vs Everton
- Burnley vs Newcastle United
- Crystal Palace vs Chelsea
- Fulham vs Wolves
- Liverpool vs Aston Villa
- Man City vs Leeds United
- Sheffield United vs Arsenal
- Spurs vs Man Utd
- West Brom vs Southampton
- West Ham vs Leicester City
Sabtu, 17 April 2021 (Pekan 32)
- Arsenal vs Fulham
- Aston Villa vs Man City
- Chelsea vs Brighton
- Everton vs Spurs
- Leeds United vs Liverpool
- Leicester City vs West Brom
- Man Utd vs Burnley
- Newcastle United vs West Ham
- Southampton vs Crystal Palace
- Wolves vs Sheffield United
Sabtu, 24 April 2021 (Pekan 33)
- Arsenal vs Everton
- Aston Villa vs West Brom
- Fulham vs Spurs
- Leeds United vs Man Utd
- Leicester City vs Crystal Palace
- Liverpool vs Newcastle United
- Man City vs Southampton
- Sheffield United vs Brighton
- West Ham vs Chelsea
- Wolves vs Burnley
Sabtu, 1 Mei 2021 (Pekan 34)
- Brighton vs Leeds United
- Burnley vs West Ham
- Chelsea vs Fulham
- Crystal Palace vs Man City
- Everton vs Aston Villa
- Man Utd vs Liverpool
- Newcastle United vs Arsenal
- Southampton vs Leicester City
- Spurs vs Sheffield United
- West Brom vs Wolves
Sabtu, 8 Mei 2021 (Pekan 35)
- Arsenal vs West Brom
- Aston Villa vs Man Utd
- Fulham vs Burnley
- Leeds United vs Spurs
- Leicester City vs Newcastle United
- Liverpool vs Southampton
- Man City vs Chelsea
- Sheffield United vs Crystal Palace
- West Ham vs Everton
- Wolves vs Brighton
Selasa, 11 Mei 2021 (Pekan 36)
- Brighton vs West Ham
- Burnley vs Leeds United
- Everton vs Sheffield United
- Man Utd vs Leicester City
- West Brom vs Liverpool
Rabu, 12 Mei 2021 (Pekan 36)
- Chelsea vs Arsenal
- Newcastle United vs Man City
- Southampton vs Fulham
- Spurs vs Wolves
- Crystal Palace vs Aston Villa
Sabtu, 15 Mei 2021 (Pekan 37)
- Brighton vs Man City
- Burnley vs Liverpool
- Chelsea vs Leicester City
- Crystal Palace vs Arsenal
- Everton vs Wolves
- Man Utd vs Fulham
- Newcastle United vs Sheffield United
- Southampton vs Leeds United
- Spurs vs Aston Villa
- West Brom vs West Ham
Minggu, 23 Mei 2021 (Pekan 38)
- Arsenal v Brighton
- Aston Villa v Chelsea
- Fulham v Newcastle United
- Leeds United v West Brom
- Leicester City v Spurs
- Liverpool v Crystal Palace
- Man City v Everton
- Sheffield United v Burnley
- West Ham v Southampton
- Wolves v Manchester United